Gene vectors focusing on CNS endothelial cells enable to govern the blood-brain barrier and to right genetic defects within the CNS. As a result of vectors based mostly on the adeno-associated virus (AAV) have a restricted capability, it’s important that the DNA sequence controlling gene expression is brief. As well as, it should be particular for endothelial cells to keep away from off-target results.
To develop improved regulatory sequences with selectivity for mind endothelial cells, we examined the transcriptional exercise of truncated promoters of 11 (mind) endothelial-specific genes together with quick regulatory parts, i.e., the woodchuck post-transcriptional regulatory ingredient (W), the CMV enhancer ingredient (C), and a fraction of the primary intron of the Tie2 gene (S), by transfecting mind endothelial cells of three species.
4 mixtures of regulatory parts and quick promoters (Cdh5, Ocln, Slc2a1, and Slco1c1) progressed by means of this in-vitro pipeline displaying appropriate exercise. When examined in mice, the regulatory sequences C-Ocln-W and C-Slc2a1-S-W enabled a stronger and extra particular gene expression in mind endothelial cells than the steadily used CAG promoter. In abstract, the brand new regulatory parts effectively management gene expression in mind endothelial cells and should assist to particularly goal the blood-brain barrier with gene remedy vectors.
From Pancreatic β–Cell Gene Networks to Novel Therapies for Kind 1 Diabetes
Completion of the Human Genome Mission enabled a novel systems- and network-level understanding of biology, however this stays to be utilized for understanding the pathogenesis of sort 1 diabetes (T1D). We suggest that defining the important thing gene regulatory networks that drive β-cell dysfunction and loss of life in T1D would possibly allow the design of therapies that focus on the core illness mechanism, specifically, the progressive lack of pancreatic β-cells.
Certainly, many profitable medicine don’t immediately goal particular person illness genes however, moderately, modulate the implications of faulty steps, focusing on proteins positioned one or two steps downstream. If we transpose this to the T1D scenario, it is smart to focus on the pathways that modulate the β-cell responses to the immune assault-in relation to indicators which will stimulate the immune response (e.g., HLA class I and chemokine overexpression and/or neoantigen expression) or inhibit the invading immune cells (e.g., PDL1 and HLA-E expression)-instead of focusing on solely the immune system, as it’s normally proposed.
Right here we talk about the significance of a give attention to β-cells in T1D, classes realized from different autoimmune illnesses, the “different splicing connection,” information mining, and drug repurposing to guard β-cells in T1D after which among the preliminary candidates below testing for β-cell safety.
Danger evaluation of leachables in cell and gene remedy utilizing a CAR-T mannequin course of
With the quickly rising subject of autologous therapies, Single-Use (SU) applied sciences are more and more utilized in personalised medication resulting from their manifold benefits. Though qualification of the beginning materials of autologous therapies such because the CAR-T course of has been highlighted, little consideration has been paid to the impact of leachables on cell-based therapies, even when latest research point out interactions of leachables with cells.
To shut this hole, this examine presents a risk-analysis of SU-material on a CAR-T course of and identifies hazards imposed by tubing supplies and leachables thereof. With a purpose to symbolize a CAR-T course of in its entirety, two check programs, specifically a lentivirus manufacturing course of and first T-cells, had been used. Whereas the results on lentivirus manufacturing are similar to these reported for antibody manufacturing processes in CHO cells, we discovered that PVC materials and corresponding leachables, i.e. plasticizer, inhibit cell development of main T-cells to a fantastic extent. Moreover, our outcomes point out that important high quality attributes are affected by the PVC materials.
Engineering genetic units for in vivo management of therapeutic T cell exercise triggered by the dietary molecule resveratrol
Chimeric antigen receptor (CAR)-engineered T cell therapies have been acknowledged as highly effective methods in most cancers immunotherapy; nevertheless, the scientific software of CAR-T is at present constrained by extreme opposed results in sufferers, brought on by extreme cytotoxic exercise and poor T cell management. Herein, we harnessed a dietary molecule resveratrol (RES)-responsive transactivator and a transrepressor to develop a repressible transgene expression (RESrep) gadget and an inducible transgene expression (RESind) gadget, respectively.
After optimization, these instruments enabled the management of CAR expression and CAR-mediated antitumor operate in engineered human cells. We demonstrated {that a} resveratrol-repressible CAR expression (RESrep-CAR) gadget can successfully inhibit T cell activation upon resveratrol administration in main T cells and a xenograft tumor mouse mannequin.
 Antibody) T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody |
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| abx415206-01mg | Abbexa | 0.1 mg | EUR 439 |
 Antibody) T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody |
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| abx415211-05mg | Abbexa | 0.5 mg | EUR 829 |
T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody |
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| abx415213-01mg | Abbexa | 0.1 mg | EUR 439 |
 Antibody) T-Cell Immunoglobulin Mucin Receptor 4 (TIM-4) Antibody |
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| abx415215-05mg | Abbexa | 0.5 mg | EUR 829 |
T-Cell Immunoglobulin Mucin Receptor 4 (TIM-4) Antibody |
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| abx415216-01mg | Abbexa | 0.1 mg | EUR 439 |
T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody |
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| abx433377-200ul | Abbexa | 200 ul | EUR 384 |
 Antibody (FITC)) T-Cell Immunoglobulin And Mucin Domain-Containing Protein 2 (TIM-2) Antibody (FITC) |
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| abx415209-01mg | Abbexa | 0.1 mg | EUR 509 |
 Polyclonal Goat anti-GST μ-form |
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| GST-ANTI-2 | Detroit R&D | 50 uL | EUR 280 |
 Antibody (FITC)) T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody (FITC) |
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| abx415205-01mg | Abbexa | 0.1 mg | EUR 509 |
 Antibody (RPE)) T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody (RPE) |
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| abx415207-100tests | Abbexa | 100 tests | EUR 592 |
 Antibody (FITC)) T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody (FITC) |
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| abx415212-01mg | Abbexa | 0.1 mg | EUR 509 |
 Antibody (RPE)) T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody (RPE) |
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| abx415214-100tests | Abbexa | 100 tests | EUR 592 |
 Antibody) Human T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody |
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| 32146-05111 | AssayPro | 150 ug | EUR 261 |
) Recombinant T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) |
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| 4-RPH854Hu01 | Cloud-Clone |
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Description: Recombinant Human Recombinant T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) expressed in: E.coli |
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 Antibody) T-Cell immunoglobulin and mucin domain-Containing protein 4 (TIMD4) Antibody |
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| 20-abx318087 | Abbexa |
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 Antibody) T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) Antibody |
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| 20-abx178542 | Abbexa |
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T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) Antibody |
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| 20-abx174727 | Abbexa |
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T-Cell immunoglobulin and mucin domain-Containing protein 4 (TIMD4) Antibody |
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| abx031021-400ul | Abbexa | 400 ul | EUR 523 |
T-Cell immunoglobulin and mucin domain-Containing protein 4 (TIMD4) Antibody |
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| abx031021-80l | Abbexa | 80 µl | EUR 286 |
, Colorimetric, Trial Size) CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric, Trial Size |
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| CBA-135-T | Cell Biolabs | 24 assays | EUR 432 |
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Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
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/HAVCR2) TIM3 (T-Cell Immunoglobulin)/HAVCR2 |
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| MO47039 | Neuromics | 100 ul | EUR 349 |
, Trial Size) CytoSelect 96-Well Cell Transformation Assay (Cell Recovery Compatible, Fluorometric), Trial Size |
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| CBA-140-T | Cell Biolabs | 24 assays | EUR 456 |
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Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
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 Rac2 Activation Assay Kit, Trial Size |
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| STA-401-2-T | Cell Biolabs | 5 assays | EUR 403 |
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Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit. |
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 Rap2 Activation Assay Kit, Trial Size |
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| STA-406-2-T | Cell Biolabs | 5 assays | EUR 403 |
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Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit. |
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 Antibody (HRP)) T-Cell immunoglobulin and mucin domain-Containing protein 4 (TIMD4) Antibody (HRP) |
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| 20-abx316455 | Abbexa |
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 Antibody (FITC)) T-Cell immunoglobulin and mucin domain-Containing protein 4 (TIMD4) Antibody (FITC) |
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| 20-abx316456 | Abbexa |
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 Antibody (Biotin)) T-Cell immunoglobulin and mucin domain-Containing protein 4 (TIMD4) Antibody (Biotin) |
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| 20-abx316457 | Abbexa |
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 Protein) Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) Protein |
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| 20-abx655199 | Abbexa |
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 Antibody (Biotin Conjugate)) Human T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody (Biotin Conjugate) |
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| 32146-05121 | AssayPro | 150 ug | EUR 369 |
) Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
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| CK57-10ug | Novoprotein | 10ug | EUR 110 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
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| CK57-1mg | Novoprotein | 1mg | EUR 1674 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
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| CK57-500ug | Novoprotein | 500ug | EUR 1186 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
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| CK57-50ug | Novoprotein | 50ug | EUR 232 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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) Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc) |
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| CM03-10ug | Novoprotein | 10ug | EUR 126 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
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Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc) |
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| CM03-1mg | Novoprotein | 1mg | EUR 1877 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
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Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc) |
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| CM03-500ug | Novoprotein | 500ug | EUR 1328 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
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Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc) |
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| CM03-50ug | Novoprotein | 50ug | EUR 232 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
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) Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
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| CM54-10ug | Novoprotein | 10ug | EUR 126 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
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| CM54-1mg | Novoprotein | 1mg | EUR 1877 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
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| CM54-500ug | Novoprotein | 500ug | EUR 1328 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
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| CM54-50ug | Novoprotein | 50ug | EUR 232 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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, Trial Size) CytoSelect 24-Well Cell Migration Assay (8 µm, Colorimetric Format), Trial Size |
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| CBA-100-T | Cell Biolabs | 4 assays | EUR 299 |
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Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 8 µm pore size is suitable for most cell types including epithelial cells, fibroblasts, and cancer cell lines. |
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, Trial Size) CytoSelect 24-Well Cell Migration Assay (8 µm, Fluorometric Format), Trial Size |
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| CBA-101-T | Cell Biolabs | 4 assays | EUR 299 |
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Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 8 µm pore size is suitable for most cell types including epithelial cells, fibroblasts, and cancer cell lines. |
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, Trial Size) CytoSelect 24-Well Cell Migration Assay (5 µm, Fluorometric Format), Trial Size |
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| CBA-102-T | Cell Biolabs | 4 assays | EUR 299 |
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Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 5 µm pore size is ideal for monocytes / macrophages. |
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, Trial Size) CytoSelect 24-Well Cell Migration Assay (3 µm, Fluorometric Format), Trial Size |
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| CBA-103-T | Cell Biolabs | 4 assays | EUR 299 |
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Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 3 µm pore size is best for the smallest cells including neutrophils and other leukocytes. |
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, Trial Size) CytoSelect 24-Well Cell Invasion Assay (Basement Membrane, Colorimetric Format), Trial Size |
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| CBA-110-T | Cell Biolabs | 4 assays | EUR 322 |
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Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with ECM matrix gel (basement membrane), a protein mix isolated from EHS tumor cells. |
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, Trial Size) CytoSelect 24-Well Cell Invasion Assay (Basement Membrane, Fluorometric Format), Trial Size |
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| CBA-111-T | Cell Biolabs | 4 assays | EUR 322 |
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Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with ECM matrix gel (basement membrane), a protein mix isolated from EHS tumor cells. |
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, Trial Size) CytoSelect 96-Well Cell Transformation Assay (Soft Agar Colony Formation), Trial Size |
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| CBA-130-T | Cell Biolabs | 24 assays | EUR 386 |
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Description: Our CytoSelect 96-Well Cell Transformation Assay (Soft Agar Colony Formation) is suitable for measuring cell transformation where no downstream analysis is required. Cells are incubated in a semisolid agar medium for 7-8 days. The cells are then solubilized, lysed and detected using the included fluorescent dye in a fluorometric plate reader. |
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 Rabbit Polyclonal antibody Anti-CRBN |
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| Anti-CRBN | ImmunoStep | 50 µg | EUR 349 |
) Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM3/HAVCR2 (C-6His) |
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| C356-10ug | Novoprotein | 10ug | EUR 121 |
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Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
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Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM3/HAVCR2 (C-6His) |
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| C356-1mg | Novoprotein | 1mg | EUR 2283 |
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Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
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Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM3/HAVCR2 (C-6His) |
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| C356-500ug | Novoprotein | 500ug | EUR 1613 |
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Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
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Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM3/HAVCR2 (C-6His) |
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| C356-50ug | Novoprotein | 50ug | EUR 263 |
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Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
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 ELISA Kit) Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
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| SEH854Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 4731.5 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) in tissue homogenates, cell lysates and other biological fluids. |
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Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
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| SEH854Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 477.3 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) in tissue homogenates, cell lysates and other biological fluids. |
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Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
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| SEH854Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 639 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) in tissue homogenates, cell lysates and other biological fluids. |
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Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
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| SEH854Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 2575.5 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) in tissue homogenates, cell lysates and other biological fluids. |
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Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
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| 4-SEH854Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
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 ELISA kit) Human T-cell immunoglobulin and mucin domain-containing protein 4(TIMD4) ELISA kit |
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| CSB-EL023546HU-24T | Cusabio | 1 plate of 24 wells | EUR 165 |
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Description: Quantitativesandwich ELISA kit for measuring Human T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Human T-cell immunoglobulin and mucin domain-containing protein 4(TIMD4) ELISA kit |
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| 1-CSB-EL023546HU | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Human T-cell immunoglobulin and mucin domain-containing protein 4(TIMD4) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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 ELISA Kit) Human T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4) ELISA Kit |
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| abx352339-96tests | Abbexa | 96 tests | EUR 786 |
 CLIA Kit) Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) CLIA Kit |
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| 20-abx495562 | Abbexa |
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Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
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| 20-abx153299 | Abbexa |
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 AssayLite Antibody (FITC Conjugate)) Human T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) AssayLite Antibody (FITC Conjugate) |
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| 32146-05141 | AssayPro | 150 ug | EUR 428 |
 AssayLite Antibody (RPE Conjugate)) Human T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) AssayLite Antibody (RPE Conjugate) |
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| 32146-05151 | AssayPro | 150 ug | EUR 428 |
 AssayLite Antibody (APC Conjugate)) Human T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) AssayLite Antibody (APC Conjugate) |
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| 32146-05161 | AssayPro | 150 ug | EUR 428 |
 AssayLite Antibody (PerCP Conjugate)) Human T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) AssayLite Antibody (PerCP Conjugate) |
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| 32146-05171 | AssayPro | 150 ug | EUR 471 |
Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
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| DLR-TIMD4-Hu-48T | DL Develop | 48T | EUR 517 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) in samples from tissue homogenates, cell lysates or other biological fluids. |
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Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
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| DLR-TIMD4-Hu-96T | DL Develop | 96T | EUR 673 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) in samples from tissue homogenates, cell lysates or other biological fluids. |
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) Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 ELISA Kit (TIMD4) |
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| RK02389 | Abclonal | 96 Tests | EUR 521 |
Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
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| RD-TIMD4-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 521 |
Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
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| RD-TIMD4-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 723 |
Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
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| RDR-TIMD4-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 544 |
Human T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
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| RDR-TIMD4-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 756 |
) Jurkat T / GFP Stable Cell (Flt1 Promoter) |
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| SC049-2 | GenTarget | 2 x 106 cell/ml x 1ml | EUR 1500 |
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Description: GFP expression stable cell line in human Jurkat T Cells with Puromycin resistance. GFP is expressed under the promoter of human Flt1 gene. |
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) ELISA kit for Human TIMD4 (T-cell immunoglobulin and mucin domain-containing protein 4) |
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| E-EL-H5515 | Elabscience Biotech | 1 plate of 96 wells | EUR 534 |
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Description: A sandwich ELISA kit for quantitative measurement of Human TIMD4 (T-cell immunoglobulin and mucin domain-containing protein 4) in samples from Serum, Plasma, Cell supernatant |
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) ELISA kit for Human TIMD4 (T-Cell Immunoglobulin And Mucin Domain Containing Protein 4) |
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| ELK4680 | ELK Biotech | 1 plate of 96 wells | EUR 432 |
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Description: A sandwich ELISA kit for detection of T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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) ELISA kit for Human T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4) |
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| KTE62326-48T | Abbkine | 48T | EUR 332 |
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Description: Quantitative sandwich ELISA for measuring Human T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4) |
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| KTE62326-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2115 |
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Description: Quantitative sandwich ELISA for measuring Human T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4) |
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| KTE62326-96T | Abbkine | 96T | EUR 539 |
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Description: Quantitative sandwich ELISA for measuring Human T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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 Anti-Mucin 2 antibody |
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| STJ16100978 | St John's Laboratory | 1 mL | EUR 597 |
 Antibody) Anti-Adiponectin Receptor 2 (mouse) Antibody |
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| A02218-2 | BosterBio | 200ug | EUR 498 |
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Description: Goat Polyclonal Adiponectin Receptor 2 (mouse) Antibody. Validated in IF, IHC and tested in Mouse. |
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 anti-CD3 T-cell |
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| 501-A-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: anti-CD3 T-cell |
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anti-CD3 T-cell |
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| 501-A-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: anti-CD3 T-cell |
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) Recombinant Human T-cell Immunoglobulin and Mucin Domain-containing Protein 4/Tim-4 (C-6His) |
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| CU18-10ug | Novoprotein | 10ug | EUR 141 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Recombinant Human T-cell Immunoglobulin and Mucin Domain-containing Protein 4/Tim-4 (C-6His) |
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| CU18-1mg | Novoprotein | 1mg | EUR 1674 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Recombinant Human T-cell Immunoglobulin and Mucin Domain-containing Protein 4/Tim-4 (C-6His) |
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| CU18-500ug | Novoprotein | 500ug | EUR 1186 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Recombinant Human T-cell Immunoglobulin and Mucin Domain-containing Protein 4/Tim-4 (C-6His) |
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| CU18-50ug | Novoprotein | 50ug | EUR 303 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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) Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His) |
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| CX71-10ug | Novoprotein | 10ug | EUR 121 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
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Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His) |
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| CX71-1mg | Novoprotein | 1mg | EUR 2283 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
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Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His) |
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| CX71-500ug | Novoprotein | 500ug | EUR 1613 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
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Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His) |
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| CX71-50ug | Novoprotein | 50ug | EUR 263 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
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 T-Pro Stacking Buffer |
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| JB03-C002 | T-Pro Biotechnology | 500ml/BT | EUR 152 |
 T-Pro MycoClean spray |
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| JT90-R002 | T-Pro Biotechnology | 500ml/BT | EUR 144 |
 CytoSelect 24-Well Wound Healing Assay, Trial Size |
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| CBA-120-T | Cell Biolabs | 6 assays | EUR 357 |
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Description: Traditionally scratch assays have been used to study cell migration, cell proliferation and wound healing. However, these assays lack a consistently defined wound gap and can result in high inter-sample variation. Our CytoSelect 24-Well Wound Healing Assay provides a much more consistent method to measure cell migration across a wound field gap in vitro. Proprietary inserts generate a consistent 0.9mm wound gap between the cells. Cells may then be treated or monitored for proliferation or migration across the wound field by imaging samples at fixed time points or by time-lapse microscopy. |
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, Trial Size) CytoSelect 96-Well In Vitro Tumor Sensitivity Assay (Soft Agar Colony Formation), Trial Size |
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| CBA-150-T | Cell Biolabs | 24 assays | EUR 403 |
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Description: Traditionally, the soft agar colony formation assay has been used to monitor anchorage-independent growth. Cells proliferate for 3-4 weeks in a semisolid culture medium, followed by tedious manual counting of colonies. Our CytoSelect 96-Well In Vitro Tumor Sensitivity Assay provides a stringent, anchorage-independent model for chemosenstivity testing and screening of potential anticancer drugs. After just 6-8 days, cell colonies are quantified using a standard colorimetric microplate reader. |
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, Trial Size) CytoSelect 96-Well Phagocytosis Assay(Zymosan Substrate), Trial Size |
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| CBA-224-T | Cell Biolabs | 20 assays | EUR 386 |
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Description: Phagocytosis can be assayed by measuring the engulfment of a cell "substrate". However, traditional assays require tedious cell counting under a microscope. Our CytoSelect 96-Well Phagocytosis Assay, Zymosan Substrate provides a more accurate, user-friendly, high-throughput alternative to the standard phagocytosis assay. The assay may be adapted for use with 24-well or 48-well plates. |
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, Trial Size) 96-Well Cellular Senescence Assay Kit (SA-?-gal Activity, Fluorometric Format), Trial Size |
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| CBA-231-T | Cell Biolabs | 24 assays | EUR 345 |
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Description: Our Cellular Senescence Activity Assay provides an efficient method to measure Senescence Associated (SA) ß-galactosidase activity. SA-ß-Gal catalyzes the hydrolysis of X-gal, which produces a blue color in senescent cells. Quantify senescence using a fluorescence plate reader. |
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 GFP ELISA Kit, Trial Size |
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| AKR-121-T | Cell Biolabs | 32 assays | EUR 392 |
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Description: Most imaging studies of rGFP are qualitative, and quantitation by FACS is time-consuming and expensive. Our GFP ELISA Kit measures green fluorescent protein in a standard microplate reader. Assay is sensitive to 30 pg/mL. |
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 OxiSelect Nitrotyrosine ELISA Kit, Trial Size |
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| STA-305-T | Cell Biolabs | 32 assays | EUR 421 |
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Description: Nitric oxide influences a variety of biological processes including cell proliferation, apoptosis, neurotoxicity and extracellular matrix remodeling. Nitric oxide reacts with superoxide to form peroxynitrite, which in turn nitrates tyrosine residues in proteins. Nitrotyrosine therefore serves as a marker for peroxynitrite action in a variety of disease states and in conditions of cellular damage and oxidative stress. Our OxiSelect Nitrotyrosine ELISA Kit provides a sensitive method to measure the formation of 3-nitrotyrosine in proteins. |
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 OxiSelect Protein Carbonyl Fluorometric Assay, Trial Size |
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| STA-307-T | Cell Biolabs | 20 assays | EUR 351 |
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Description: The most common products of protein oxidation in biological samples are the carbonyl derivatives of proline, lysine, arginine and threonine residues. Such derivatives are chemically stable and serve as markers for oxidative stress in most types of reactive oxygen species. Our OxiSelect Protein Carbonyl Fluorometric Assay Kit provides a rapid, efficient method for the detection of protein carbonyl residues. The fluorescence plate-based format provides a convenient system for direct measurement of protein carbonyl content. |
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 OxiSelect Protein Carbonyl Immunoblot Kit, Trial Size |
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| STA-308-T | Cell Biolabs | 4 blots | EUR 264 |
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Description: The most common products of protein oxidation in biological samples are the carbonyl derivatives of proline, lysine, arginine and threonine residues. Such derivatives are chemically stable and serve as markers for oxidative stress in most types of reactive oxygen species. Our OxiSelect Protein Carbonyl Immunoblot Kit provides a rapid, efficient method for the detection of protein carbonyl residues. The immunoblot format provides a convenient way to compare oxidized and non-oxidized protein fingerprints. |
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 OxiSelect Protein Carbonyl ELISA Kit, Trial Size |
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| STA-310-T | Cell Biolabs | 32 assays | EUR 421 |
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Description: The most common products of protein oxidation in biological samples are the carbonyl derivatives of proline, lysine, arginine and threonine residues. Such derivatives are chemically stable and serve as markers for oxidative stress in most types of reactive oxygen species. Our OxiSelect Protein Carbonyl ELISA Kit provides a rapid, efficient method for the detection of protein carbonyl residues. The ELISA format is perfect for higher throughput and high sensitivity; we have eliminated concentration and precipitation steps allowing greater sample retention. |
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 Assay Kit, Trial Size) OxiSelect Total Glutathione (GSSG/GSH) Assay Kit, Trial Size |
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| STA-312-T | Cell Biolabs | 20 assays | EUR 282 |
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Description: The OxiSelect Total Glutathione Assay Kit is a quantitative assay for measuring the total glutathione content within a sample (GSH/GSSG). Glutathione Reductase reduces oxidized glutathione (GSSG) to reduced glutathione (GSH) in the presence of NADPH. Subsequently, the chromogen reacts with the thiol group of GSH to produce a colored compound that absorbs at 405 nm. The total glutathione content in unknown samples is determined by comparison with the predetermined glutathione standard curve. The rate of chromophore production is proportional to the concentration of glutathione within the sample. The rate can be determined from the absorbance change over time. Metaphosphoric acid is provided to remove interfering proteins or enzymes from samples. |
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, Trial Size) OxiSelect Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation), Trial Size |
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| STA-320-T | Cell Biolabs | 32 assays | EUR 508 |
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Description: Among numerous types of oxidative DNA damage, 8-hydroxydeoxyguanosine (8-OHdG) is a ubiquitous marker of oxidative stress. 8-OHdG, one of the byproducts of oxidative DNA damage, is physiologically formed and enhanced by chemical carcinogens. Our OxiSelect Oxidative DNA Damage ELISA Kit (8-hydroxydeoxyguanosine assay) provides a powerful method for rapid, sensitive quantitation of 8-OHdG in DNA samples. |
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 Staining Kit, Trial Size) OxiSelect DNA Double Strand Break (DSB) Staining Kit, Trial Size |
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| STA-321-T | Cell Biolabs | 20 assays | EUR 351 |
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Description: Double-strand breaks (DSB) in DNA are among the most dangerous types of DNA damage occuring within cells. One of the earliest cellular responses to double-strand breaks is the phosphorylation of a histone variant, H2AX, at the sites of DNA damage. Within seconds Ser139 is phosphorylated when DSBs are induced in mammalian cells. Phosphorylation of this serine residue causes chromatin condensation and appears to play a critical role in the recruitment of repair or damage-signaling factors to the DNA damage sites. The OxiSelect DNA Double-Strand Break Staining Kit provides an easy-to-use method for detecting the presence of DSBs in cells cultured in microtiter plates. Double strand breaks can be detected in just a few hours by immunofluorescence staining of the phosphorylated histone H2AX. |
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, Trial Size) OxiSelect UV-Induced DNA Damage ELISA Kit (CPD Quantitation), Trial Size |
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| STA-322-T | Cell Biolabs | 32 assays | EUR 351 |
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Description: Our OxiSelect UV-Induced DNA Damage ELISA Kit measures the formation of cyclobutane pyrimidine dimers (CPD) in DNA isolated from cells or tissues. Standards or unknown DNA samples are first heat denatured before adsorbed onto a 96-well DNA binding plate. The sample or standard are then probed with an anti-CPD antibody, followed by an HRP conjugated secondary antibody. |
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, Trial Size) OxiSelect UV-Induced DNA Damage ELISA Kit (6-4PP Quantitation), Trial Size |
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| STA-323-T | Cell Biolabs | 32 assays | EUR 351 |
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Description: Our OxiSelect UV-Induced DNA Damage ELISA Kit measures 6-4PP formation in DNA isolated from cells or tissue. Standards or unknown DNA samples are first heat denatured before adsorbed onto a 96-well DNA binding plate. The sample or standard is then probed with an anti-6-4PP antibody, followed by an HRP conjugated secondary antibody. |
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, Trial Size) OxiSelect Oxidative DNA Damage Quantitation Kit (AP Sites), Trial Size |
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| STA-324-T | Cell Biolabs | 10 assays | EUR 415 |
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Description: DNA damage can manifest in the formation of apurinic or apyrimidinic (AP or abasic) sites. Such spontaneous base loss in mammalian cells has been estimated at between 50,000 and 200,000 sites per day. Unrepaired abasic sites can inhibit transcription and may be mutagenic. Our OxiSelect Oxidative DNA Damage Quantitation Kit provides a simple, user-friendly method for the quantitaiton DNA damage in the form of abasic sites. The assay uses an Aldehyde Reactive Probe (ARP) to specifically react with an aldehyde group on the open ring of the AP site. This allows the AP site to be labeled with Biotin, followed by detection with Streptavidin-Enzyme conjugate. |
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, Trial Size) OxiSelect Oxidative RNA Damage ELISA Kit (8-OHG Quantitation), Trial Size |
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| STA-325-T | Cell Biolabs | 32 assays | EUR 508 |
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Description: Recently oxidative RNA damage has been described in conjunction with a wide variety of neurological diseases including Alzheimer?s disease, Parkinson?s disease, Dementia with Lewy Bodies, prion disease, and subacute sclerosing panencephalitis. We have developed an easy-to-use ELISA for the detection of the most common marker of RNA damage: 8-hydroxyguanosine (8-OHG). |
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, Trial Size) OxiSelect Cellular UV-Induced DNA Damage ELISA Kit (CPD), Trial Size |
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| STA-326-T | Cell Biolabs | 32 assays | EUR 351 |
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Description: Our OxiSelect Cellular UV-Induced DNA Damage ELISA Kit mesaures the formation of cyclobutane pyrimidine dimers (CPD) in intact cells. Cells are first seeded in a 96-well tissue culture plate. Wells are then UV irradiated to induce DNA damage. After fixation and denaturation, cells containing the DNA lesions are probed with an anti-CPD antibody, followed by an HRP conjugated secondary antibody. |
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, Trial Size) OxiSelect Cellular UV-Induced DNA Damage Staining Kit (CPD), Trial Size |
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| STA-327-T | Cell Biolabs | 32 assays | EUR 351 |
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Description: Our OxiSelect Cellular UV-Induced DNA Damage Staining Kit measures the formation of cyclobutane pyrimidine dimers (CPD) by immunofluorescence. Cells are first seeded in a 96-well tissue culture plate. Wells are then UV irradiated to induce DNA damage. After fixation and denaturation, cells containing the DNA lesions are probed with an anti-CPD antibody, followed by a FITC conjugated secondary antibody. The unbound secondary antibody is removed during a wash step, and stained cells can then be visualized with a fluorescence microscope. |
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, Trial Size) OxiSelect Cellular UV-Induced DNA Damage ELISA Kit (6-4PP), Trial Size |
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| STA-328-T | Cell Biolabs | 32 assays | EUR 351 |
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Description: Our OxiSelect Cellular UV-Induced DNA Damage ELISA Kit measures the formation of 6-4PP in intact cells in a 96-well ELISA plate-based format. Cells are first seeded in a 96-well tissue culture plate. Wells are then UV irradiated to induce DNA damage. After fixation and denaturation, cells containing the DNA lesions are probed with an anti-6-4PP antibody, followed by an HRP conjugated secondary antibody. |
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, Trial Size) OxiSelect Cellular UV-Induced DNA Damage Staining Kit (6-4PP), Trial Size |
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| STA-329-T | Cell Biolabs | 32 assays | EUR 351 |
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Description: Our OxiSelect Cellular UV-Induced DNA Damage Staining Kit measures the formation of 6-4PP structures in DNA by immunofluorescence. Cells are first seeded in a 96-well tissue culture plate. Wells are then UV irradiated to induce DNA damage. After fixation and denaturation, cells containing the DNA lesions are probed with an anti-6-4PP antibody, followed by a FITC conjugated secondary antibody. The unbound secondary antibody is removed during a wash step, and stained cells can then be visualized with a fluorescence microscope. |
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, Trial Size) OxiSelect TBARS Assay Kit (MDA Quantitation), Trial Size |
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| STA-330-T | Cell Biolabs | 20 assays | EUR 340 |
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Description: The TBARS (Thiobarbituric Acid Reactive Substances) assay is well-established for screening and monitoring lipid peroxidation. MDA forms a 1:2 adduct with thiobarbituric acid; the MDA-TBA adduct can then be measured. Our OxiSelect TBARS Assay Kit provides a much more user-friendly protocol to measure the MDA-TBA adduct. Reaction volumes are much smaller than the traditional assay, so much less sample is required. Also, reactions can be performed in standard polypropylene tubes - no glass tubes or glass marbles are required. Important Note: MDA adducts are not stable long term. For best results test all samples immediately upon collection, or freeze them at -80ºC for up to one month. MDA may be degraded in samples that have been frozen for longer periods; in such cases more reliable results may be obtained from more stable markers of oxidative stress such as protein carbonyl, 8-OHdG or 4-HNE. |
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 OxiSelect 8-iso-Prostaglandin F2a ELISA Kit, Trial Size |
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| STA-337-T | Cell Biolabs | 32 assays | EUR 328 |
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Description: 8-iso-Prostaglandin F2alpha (8-isoprostane) is a stable by-product of lipid peroxides generated during oxidative stress. Our OxiSelect 8-Isoprostane Assay Kit provides a convenient method for absolute quantitation in just a few hours. The 8-Isoprostane ELISA is suitable for a variety of sample types including urine, plasma, and cell lysates. |
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 OxiSelect Catalase Activity Assay Kit, Fluorometric, Trial Size |
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| STA-339-T | Cell Biolabs | 50 assays | EUR 398 |
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Description: Catalase is a ubiquitous enzyme that destroys hydrogen peroxides formed during oxidative stress. Our OxiSelect Catalase Activity Assay Kit measures catalase activity in less than one hour from a variety of samples including blood, cells and tissues. Each kit provides sufficient reagents to perform up to 500 assays in a 96-well microtiter plate. This includes blanks, catalase standards and unknown samples. The OxiSelect Catalase Activity Assay Kit (Fluorometric) provides a 40-fold increase in sensitivity compared to our colorimetric assay. |
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 OxiSelect Superoxide Dismutase Activity Assay, Trial Size |
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| STA-340-T | Cell Biolabs | 20 assays | EUR 345 |
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Description: Superoxide dismutase (SOD), which catalyzes the dismutation of the superoxide anion into hydrogen peroxide and molecular oxygen, is one of the most important antioxidant enzymes. SOD enzymes are classified into three groups: cytosolic CuZn-SOD, mitochondrial Mn-SOD, and extracellular Ec-SOD. Our OxiSelect Superoxide Dismutase Activity Assay uses a xanthine/xanthine oxidase (XOD) system to generate superoxide anions and a chromagen to produce a water-soluble formazan dye upon reduction by superoxide anions. The superoxide dismutase activity is determined as the inhibition or reduction of chromagen. |
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, Trial Size) OxiSelect Catalase Activity Assay Kit (Colorimetric), Trial Size |
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| STA-341-T | Cell Biolabs | 20 assays | EUR 363 |
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Description: Catalase is a ubiquitous enzyme that destroys hydrogen peroxides formed during oxidative stress. Our OxiSelect Catalase Activity Assay Kits measure catalase activity in less than one hour from a variety of samples including blood, cells and tissues. Each kit provides sufficient reagents to perform up to 100 assays in a 96-well microtiter plate, or 50 assays in microcentrifuge tubes. This includes blanks, catalase standards and unknown samples. Direct spectrophotometric detection of catalase activity with ultraviolet light can cause interference from proteins and other biological components. The OxiSelect Catalase Activity Assay Kit (Colorimetric) utilizes visible light (520 nm), which reduces sample interference. The OxiSelect Catalase Activity Assay Kit (Fluorometric) provides a 40-fold increase in sensitivity compared to our colorimetric assay. |
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, Trial Size) OxiSelect Intracellular ROS Assay Kit (Green Fluorescence), Trial Size |
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| STA-342-T | Cell Biolabs | 20 assays | EUR 345 |
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Description: The OxiSelect ROS Assay Kit is a cell-based assay for measuring hydroxyl, peroxyl, and other reactive oxygen species activity within a cell. The assay employs the cell-permeable fluorogenic probe DCFH-DA, which diffuses into cells and is deacetylcated by cellular esterases into the non-fluorescent DCFH (Figure 1). In the presence of ROS, DCFH is rapidly oxidized to highly fluorescent DCF. Fluorescence is read on a standard fluorometric plate reader. |
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, Trial Size) OxiSelect Hydrogen Peroxide/Peroxidase Assay Kit (Fluorometric), Trial Size |
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| STA-344-T | Cell Biolabs | 50 assays | EUR 287 |
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Description: The OxiSelect Hydrogen Peroxide/Peroxidase Assay Kit is a sensitive quantitative fluorometric assay for hydrogen peroxide or peroxidase. In the presence of HRP, ADHP reacts with H2O2 in a 1:1 stoichiometry to produce highly fluorescent Resorufin. The Resorufin product can be easily read by a fluorescence microplate reader with an excitation of 530-560 nm and an emission of 590 nm, or for absorbance at 560 nm. Fluorescence values are proportional to the H2O2 or peroxidase levels within the samples. The H2O2 or peroxidase content in unknown samples is determined by comparison with its respective standard curve. |
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 Activity Assay, Trial Size) OxiSelect Oxygen Radical Antioxidant Capacity (ORAC) Activity Assay, Trial Size |
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| STA-345-T | Cell Biolabs | 48 assays | EUR 316 |
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Description: The ORAC assay is a powerful tool to measure the antioxidant capacity of biomolecules. Our OxiSelect ORAC Activity Assay measures this capacity in less than 2 hours from a wide variety of sample types. |
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Moreover, we exhibit how a resveratrol-inducible CAR expression (RESind-CAR) gadget can obtain fine-tuned and reversible management over T cell activation through a resveratrol-titratable mechanism. Moreover, our outcomes revealed that the presence of RES can activate RESind-CAR T cells with robust anticancer cytotoxicity towards cells in vitro and in vivo. Our examine demonstrates the utility of RESrep and RESind units as efficient instruments for transgene expression and illustrates the potential of RESrep-CAR and RESind-CAR units to boost affected person security in precision most cancers immunotherapies.