The US Meals and Drug Administration (FDA) regulates manufacturing and testing of superior therapeutic medicinal merchandise (ATMPs) to make sure the security of every product for human use. Gold normal sterility testing (USP<71>) and different blood tradition methods have main limitations for the detection of fungal contaminants. On this research, we evaluated the efficiency of iLYM media (designed initially for the meals and beverage trade) to evaluate its potential to be used within the biopharmaceutical subject for ATMP sterility testing.
We performed a parallel analysis of 4 totally different take a look at methods (USP<71>, BacT/ALERT, BACTEC, and Sabouraud Dextrose Agar [SDA] tradition), three totally different bottle media formulations (iLYM, iFA+, and Myco/F Lytic), and two incubation temperatures (22.5°C and 32.5-35°C) utilizing a various set of fungi (n=51) remoted from NIH cleanroom environments and former product contaminants. Moreover, we evaluated the impact of agitation versus “delayed entry” static pre-incubation on take a look at sensitivity and time to detection (TTD). General, delayed entry of bottles onto the BacT/ALERT or BACTEC devices (with agitation) didn’t enhance take a look at efficiency.
USP<71> and SDA tradition continued to considerably outperform every automated tradition situation alone. Nonetheless, we present for the primary time, {that a} closed-system, dual-bottle mixture of iLYM 22.5°C and iFA+ 32.5°C can present excessive fungal sensitivity, statistically corresponding to USP<71>, when examined in opposition to a various vary of environmental fungi. Our research fills a much-needed hole in biopharmaceutical testing and provides a good testing algorithm that maximizes bacterial and fungal take a look at sensitivity while minimizing threat of product contamination related to laboratory dealing with.
Gene-Edited Interleukin CAR-T Cells Remedy within the Remedy of Malignancies: Current and Future
Lately, chimeric antigen receptor T cells (CAR-T cells) have been confronted with the issues of weak proliferation and poor persistence within the remedy of some malignancies. Researchers have been attempting to excellent the perform of CAR-T by genetically modifying its construction. Along with the participation of T cell receptor (TCR) and costimulatory alerts, immune cytokines additionally exert a decisive function within the activation and proliferation of T cells.
Due to this fact, genetic engineering methods had been used to generate cytokines to boost tumor killing perform of CAR-T cells. When CAR-T cells are in touch with goal tumor tissue, the proliferation means and persistence of T cells might be improved by structurally or inductively releasing immunoregulatory molecules to the tumor area.
There are numerous CAR-T cells research on gene-edited cytokines, and the most typical cytokines concerned are interleukins (IL-7, IL-12, IL-15, IL-18, IL-21, IL-23). Strategies for the development of gene-edited interleukin CAR-T cells embrace co-expression of single interleukin, two interleukin, interleukin mixed with different cytokines, interleukin receptors, interleukin subunits, and fusion inverted cytokine receptors (ICR).
Preclinical and medical trials have yielded constructive outcomes, and lots of extra are underneath manner. By studying numerous literatures, we summarized the purposeful traits of some members of the interleukin household associated to tumor immunotherapy, and described the analysis standing of gene-edited interleukin CAR-T cells within the remedy of malignant tumors. The target is to discover the optimized technique of gene edited interleukin-CAR-T cell perform.
Improved Supply Strategies for Gene Remedy and Cell Transplantation in Parkinson’s Illness
Quite a lot of cell transplantation and gene remedy trials have been carried out during the last three many years in an effort to revive perform in Parkinson’s illness. A lot has been realized about optimizing supply strategies for these therapeutics. That is significantly true in gene remedy, which has predominated the medical trial panorama in recent times; nonetheless, cell transplantation for Parkinson’s illness is at present present process a renaissance.
Improvements reminiscent of cannula design, iMRI-guided surgical procedure and an evolution in supply technique has radically modified the way in which investigators method medical trial design. Future therapeutic methods could make use of newer supply strategies reminiscent of chronically implanted infusion gadgets and focal opening of the blood mind barrier with centered ultrasound.
SLC4A11 and MFSD3 Gene Expression Adjustments in Deoxynivalenol Handled IPEC-J2 Cells
Deoxynivalenol (DON) brought about critical cytotoxicity for animal cells. Nonetheless, genes concerned in regulating DON toxicity and the underlying molecular mechanisms stay largely unknown. This research explored the function of SLC4A11 and MFSD3 in assuaging DON toxicity and analyzed the DNA methylation adjustments of those two genes.
Viability and cell cycle evaluation confirmed that DON publicity decreased the IPEC-J2 viability (P < 0.01), blocked the cell cycle within the G2/M part (P < 0.01), and elevated the speed of apoptosis (P < 0.05). Expression of the SLC4A11 and MFSD3 genes was considerably downregulated upon DON publicity (P < 0.01).
Overexpression of SLC4A11 and MFSD3 can improve the cell viability (P < 0.01). DNA methylation assays indicated that promoter methylation of SLC4A11 (mC-1 and mC-23) and MFSD3 (mC-1 and mC-12) had been considerably increased in contrast with these within the controls and correlated negatively with mRNA expression (P < 0.05).
 AssayMax ELISA Kit) Mouse Stem Cell Factor (SCF) AssayMax ELISA Kit |
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| EMS1001-1 | AssayPro | 96 Well Plate | EUR 396 |
) Mouse Nanog Stem Cell Differentiation Reporter (pGreenZeo, plasmid) |
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| SR10031PA-1 | SBI | 10 ug | EUR 1749 |
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) Mouse Nanog Stem Cell Differentiation Reporter (pGreenZeo, pre-packaged) |
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| SR10031VA-1 | SBI | >2 x 10^6 IFUs | EUR 755 |
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 Polyclonal Goat anti-GST α-form |
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| GST-ANTI-1 | Detroit R&D | 50 uL | EUR 280 |
 SCF Stem Cell Factor Human Recombinant Protein |
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| PROTP21583-1 | BosterBio | Regular: 10ug | EUR 317 |
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Description: Stem Cell Factor Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 165 amino acids and having a molecular mass of 18409 Dalton. ;The SCF is purified by proprietary chromatographic techniques. |
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) StemBoost? Neural Stem Cell Reprogramming Cocktail (100X) |
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| S238-1 | Biovision | EUR 185 | |
 SCA-1 Antibody |
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| 47996-100ul | SAB | 100ul | EUR 333 |
SCA-1 Antibody |
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| 47996-50ul | SAB | 50ul | EUR 239 |
 AssayMax ELISA Kit) Human Stem Cell Factor (SCF) AssayMax ELISA Kit |
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| ES1001-1 | AssayPro | 96 Well Plate | EUR 396 |
 SCA-1 Conjugated Antibody |
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| C47996 | SAB | 100ul | EUR 397 |
) Mouse Prostate stem cell antigen (Psca) |
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| 1-CSB-YP018840MO | Cusabio |
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Description: Recombinant Mouse Prostate stem cell antigen(Psca) expressed in Yeast |
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 Anti-Periphilin 1 Antibody |
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| A06996-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse. |
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 Anti-Lyl-1 Antibody |
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| A07491-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat. |
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 Anti-GLI-1 Antibody |
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| A07972-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for GLI-1 Antibody (ACSS1) detection. Tested with WB in Human, Mouse, Rat. |
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 Anti-Cerebellin 1 Antibody |
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| A09176-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for Cerebellin 1 Antibody (CBLN1) detection. Tested with WB in Human, Mouse, Rat. |
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 Anti-DOC-1 Antibody |
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| A09467-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for DOC-1 Antibody (CDK2AP1) detection. Tested with WB in Human, Mouse. |
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 Anti-NPDC-1 Antibody |
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| A12846-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for NPDC-1 Antibody (NPDC1) detection. Tested with WB in Human, Mouse, Rat. |
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 Anti-CNG-1 Antibody |
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| A05494-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat. |
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 Anti-Flk-1 Antibody |
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| A00901-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse. |
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 Anti-EDG-1 Antibody |
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| A01502-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat. |
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 Anti-ROBO-1 Antibody |
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| A01530-1 | BosterBio | 100ug | EUR 455 |
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Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
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 Anti-Bag-1 Antibody |
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| A02423-1 | BosterBio | 50 ul | EUR 397 |
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Description: Rabbit Polyclonal Bag-1 Antibody. Validated in IP, IHC and tested in Bovine, Canine, Human, Mouse, Rat. |
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 Anti-TUB 1 Antibody |
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| A02917-1 | BosterBio | 100ug/vial | EUR 294 |
 Anti-Dok-1 Antibody |
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| A03039-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for Dok-1 Antibody (DOK1) detection.tested for WB in Human, Mouse, Rat. |
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 Anti-TFIIIB90-1 Antibody |
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| A03761-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse. |
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 Anti-Atrophin-1 Antibody |
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| A03828-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat. |
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 Anti-PARP-1 Antibody |
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| A00122-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse. |
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 Anti-Presenilin 1 Antibody |
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| A00138-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat. |
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 Anti-PAI-1 Antibody |
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| A00637-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat. |
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) Anti-HO-1 Monoclonal Antibody (HO-1-2) |
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| M00253-1 | BosterBio | 1mg | EUR 397 |
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Description: Mouse Monoclonal HO-1 Antibody (HO-1-2). Validated in Flow Cytometry, IHC, WB and tested in Human, Mouse, Rat. |
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 Anti-Pyrophosphatase 1/PPA1 Antibody |
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| A07485-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-TCP-1 eta Antibody |
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| A08169-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for TCP-1 eta Antibody (CCT7) detection. Tested with WB in Human, Mouse, Rat. |
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 Anti-Relaxin 1/RLN1 Antibody |
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| A08367-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-TCP-1 zeta Antibody |
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| A09373-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for TCP-1 zeta Antibody (CCT6A) detection.tested for WB in Human, Mouse, Rat. |
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 Anti-CHST8/Galnac4St 1 Antibody |
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| A10989-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal CHST8/Galnac4St 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
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 Anti-Musashi 1/Msi1 Antibody |
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| A05052-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-LOX-1/OLR1 Antibody |
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| A00760-1 | BosterBio | 100ug/vial | EUR 294 |
 Anti-Syndecan-1/SDC1 Antibody |
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| A00991-1 | BosterBio | 100ug/vial | EUR 294 |
 Anti-IRAK-1/IRAK1 Antibody |
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| A01021-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-Neurexin 1/NRXN1 Antibody |
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| A01490-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-Hexokinase 1/HK1 Antibody |
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| A01504-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-Synaptotagmin 1/SYT1 Antibody |
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| A02314-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-Syntenin-1 Monoclonal Antibody |
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| A02475-1 | BosterBio | 100ul | EUR 397 |
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Description: Mouse Monoclonal Antibody for Syntenin-1 Antibody (SDCBP) detection. Tested with WB in Human, Rat, Dog, Pig. |
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 Anti-Dsg1/Desmoglein 1 Antibody |
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| A02655-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for Dsg1 Antibody (DSG1) detection.tested for IHC, WB in Human, Mouse, Rat. |
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 Anti-CAF-1 p150 Antibody |
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| A02732-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for CAF-1 p150 Antibody (CHAF1A) detection. Tested with WB in Human, Mouse. |
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 Anti-Talin 1/TLN1 Antibody |
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| A02859-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-Islet 1/ISL1 Antibody |
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| A02969-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-TNF Receptor 1 Antibody |
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| A00294-1 | BosterBio | 200ug | EUR 522 |
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Description: Rabbit Polyclonal TNF Receptor 1 Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat. |
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 Anti-Galectin 1/Lgals1 Antibody |
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| A00470-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-Angiopoietin 1/ANGPT1 Antibody |
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| PA1333-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-Presenilin 1 Monoclonal Antibody |
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| M00138-1 | BosterBio | 100ug | EUR 397 |
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Description: Rabbit Monoclonal Presenilin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
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 Anti-Galectin 1 Monoclonal Antibody |
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| M00470-1 | BosterBio | 100ug | EUR 397 |
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Description: Rabbit Monoclonal Galectin 1 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat. |
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 Anti-DJ-1 Monoclonal Antibody |
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| M00757-1 | BosterBio | 100ul | EUR 397 |
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Description: Mouse Monoclonal DJ-1 Antibody. Validated in IHC, WB and tested in Bovine, Human. |
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 Anti-Enolase 1 Monoclonal Antibody |
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| M01250-1 | BosterBio | 100ul | EUR 397 |
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Description: Anti-Enolase 1 Monoclonal Antibody tested in WB, IF, ICC, IHC, reactive to Human, rat, mouse, cow, pig, horse |
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 Anti-Dynamin 1 Monoclonal Antibody |
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| M02536-1 | BosterBio | 100ug | EUR 397 |
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Description: Rabbit Monoclonal Dynamin 1 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat. |
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 Anti-Esrp-1 Monoclonal Antibody |
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| M06068-1 | BosterBio | 100uL | EUR 443 |
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Description: Mouse Monoclonal Esrp-1 Antibody. Validated in WB and tested in Human. |
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 Anti-Galectin 1/LGALS1 Antibody |
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| PB9240-1 | BosterBio | 100ug/vial | EUR 334 |
, 2mg/mL) CF350 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
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| 20245-1 | Biotium | 50uL | EUR 149 |
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Description: Minimum order quantity: 1 unit of 50uL |
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, 2mg/mL) CF488A Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
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| 20246-1 | Biotium | 50uL | EUR 149 |
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Description: Minimum order quantity: 1 unit of 50uL |
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, 2mg/mL) CF555 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
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| 20247-1 | Biotium | 50uL | EUR 149 |
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Description: Minimum order quantity: 1 unit of 50uL |
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, 2mg/mL) CF568 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
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| 20248-1 | Biotium | 50uL | EUR 149 |
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Description: Minimum order quantity: 1 unit of 50uL |
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, 2mg/mL) CF594 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
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| 20249-1 | Biotium | 50uL | EUR 149 |
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Description: Minimum order quantity: 1 unit of 50uL |
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, 2mg/mL) CF633 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
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| 20250-1 | Biotium | 50uL | EUR 149 |
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Description: Minimum order quantity: 1 unit of 50uL |
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, 2mg/mL) CF640R Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
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| 20251-1 | Biotium | 50uL | EUR 149 |
|
Description: Minimum order quantity: 1 unit of 50uL |
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, 2mg/mL) CF647 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
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| 20252-1 | Biotium | 50uL | EUR 149 |
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Description: Minimum order quantity: 1 unit of 50uL |
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, 2mg/mL) CF680 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
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| 20253-1 | Biotium | 50uL | EUR 161 |
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Description: Minimum order quantity: 1 unit of 50uL |
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, 2mg/mL) CF770 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
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| 20254-1 | Biotium | 50uL | EUR 161 |
|
Description: Minimum order quantity: 1 unit of 50uL |
|||
, 2mg/mL) CF543 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
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| 20325-1 | Biotium | 50uL | EUR 149 |
|
Description: Minimum order quantity: 1 unit of 50uL |
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 Prostate Stem Cell Antigen Antibody |
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| 33476-100ul | SAB | 100ul | EUR 252 |
Prostate Stem Cell Antigen Antibody |
|||
| 33476-50ul | SAB | 50ul | EUR 187 |
Prostate Stem Cell Antigen Antibody |
|||
| DF8709 | Affbiotech | 200ul | EUR 304 |
|
Description: Prostate Stem Cell Antigen Antibody detects endogenous levels of total Prostate Stem Cell Antigen. |
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Prostate Stem Cell Antigen Antibody |
|||
| ABD8709 | Lifescience Market | 100 ug | EUR 438 |
) Hemokinin 1 (mouse) |
|||
| B5127-1 | ApexBio | 1 mg | EUR 321 |
 AXMIR-1 RNA oligo anti-miRNA-1-3p with Xmotif |
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| AXMIR-1 | SBI | 10 reactions | EUR 438 |
|
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 Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 |
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| M04431-1 | BosterBio | 100uL | EUR 385 |
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Description: Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 tested in WB, IHC, reactive to Human |
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 Anti-CELSR3/Flamingo Homolog 1 Antibody |
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| A07204-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal CELSR3/Flamingo Homolog 1 Antibody. Validated in IF and tested in Human, Mouse, Rat. |
|||
 Anti-LPCAT2/Acyltransferase Like 1 Antibody |
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| A07471-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal LPCAT2/Acyltransferase Like 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
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 Anti-Hyaluronan synthase 1/HAS1 Antibody |
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| A04784-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-Liver Carboxylesterase 1/CES1 Antibody |
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| A01741-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-EBP50/NHERF-1/SLC9A3R1 Antibody |
|||
| A02427-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-IL1R2/Il 1 Rii Antibody |
|||
| A03106-1 | BosterBio | 1 ml | EUR 397 |
|
Description: Rabbit Polyclonal IL1R2/Il 1 Rii Antibody. Validated in IP, WB and tested in Human. |
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 Anti-HIF-1 alpha/HIF1A Antibody |
|||
| A00013-1 | BosterBio | 100ug/vial | EUR 294 |
 Antibody) Anti-Cleaved-Notch 1 (V1754) Antibody |
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| A00033-1 | BosterBio | 100ul | EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Cleaved-Notch 1 (V1754) Antibody (NOTCH1) detection.tested for WB in Human, Mouse, Rat. |
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 Antibody) Anti-HDAC-1 (C-terminus) Antibody |
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| A00256-1 | BosterBio | 100uL | EUR 443 |
|
Description: Rabbit Polyclonal HDAC-1 (C-terminus) Antibody. Validated in IF, IHC, WB and tested in Human. |
|||
 Anti-VEGF Receptor 1/FLT1 Antibody |
|||
| A00534-1 | BosterBio | 100ug/vial | EUR 294 |
 Anti-Integrin alpha 1/ITGA1 Antibody |
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| PA1045-1 | BosterBio | 100ug/vial | EUR 334 |
/CASP1 Antibody) Anti-Caspase-1(P20)/CASP1 Antibody |
|||
| PA1440-1 | BosterBio | 100ug/vial | EUR 294 |
Anti-VEGF Receptor 1/FLT1 Antibody |
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| PA1966-1 | BosterBio | 100ug/vial | EUR 294 |
 Anti-Sumo 1 Rabbit Monoclonal Antibody |
|||
| M00631-1 | BosterBio | 100ug/vial | EUR 397 |
|
Description: Rabbit Monoclonal Sumo 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human, Mouse, Rat. |
|||
 Anti-Cytokeratin 1 Rabbit Monoclonal Antibody |
|||
| M01639-1 | BosterBio | 100ug/vial | EUR 397 |
|
Description: Rabbit Monoclonal Cytokeratin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
|||
) Anti-Mitofusin 1 Antibody (monoclonal, 3H3) |
|||
| M02172-1 | BosterBio | 100ug/vial | EUR 294 |
 Antibody) Anti-Phospho-Beclin-1 (Ser295) Antibody |
|||
| P00327-1 | BosterBio | 100ul | EUR 398 |
|
Description: Rabbit Polyclonal Phospho-Beclin-1 (Ser295) Antibody. Validated in WB and tested in Human. |
|||
 Antibody) Anti-Phospho-Raf-1 (Ser642) Antibody |
|||
| P00446-1 | BosterBio | 100ul | EUR 398 |
|
Description: Rabbit Polyclonal Phospho-Raf-1 (Ser642) Antibody. Validated in WB and tested in Human, Rat. |
|||
 TINAGL1 Human, Tubulointerstitial Nephritis Antigen Like 1 Human Recombinant Protein, Sf9 |
|||
| PROTQ9GZM7-1 | BosterBio | Regular: 5ug | EUR 317 |
|
Description: TINAGL1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 455 amino acids (22-467a.a.) and having a molecular mass of 51.2kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). TINAGL1 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques. |
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 Anti-TTF-1 |
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| DB-089-1 | DB Biotech | 1 ml | EUR 750 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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 (Hematopoietic Stem Cell Marker); Clone 3D3 (Concentrate)) Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker); Clone 3D3 (Concentrate) |
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| RA0264-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125 |
 AssayMax ELISA Kit) Human T-Cell Antigen CD7 (CD7) AssayMax ELISA Kit |
|||
| EC3502-1 | AssayPro | 96 Well Plate | EUR 477 |
 Anti-GABA B Receptor 1/GABBR1 Antibody |
|||
| A07297-1 | BosterBio | 100ug/vial | EUR 294 |
 Anti-Vangl1/Vang Like Protein 1 Antibody |
|||
| A07587-1 | BosterBio | 100ul | EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Vangl1 Antibody (VANGL1) detection. Tested with WB in Human, Mouse. |
|||
 Anti-E74 like factor 1/ELF1 Antibody |
|||
| A03187-1 | BosterBio | 100ug/vial | EUR 294 |
 Anti-Angiotensin Converting Enzyme 1/ACE Antibody |
|||
| PA2196-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-HMGB1/Hmg 1 Rabbit Monoclonal Antibody |
|||
| M00066-1 | BosterBio | 100ug/vial | EUR 397 |
|
Description: Rabbit Monoclonal HMGB1/Hmg 1 Antibody. Validated in Flow Cytometry, IF, IHC, ICC, WB and tested in Human, Mouse, Rat. |
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 Anti-p27 KIP 1 Rabbit Monoclonal Antibody |
|||
| M00173-1 | BosterBio | 100ug/vial | EUR 397 |
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Description: Anti-p27 KIP 1 Rabbit Monoclonal Antibody tested for Flow Cytometry, IP, IF, IHC, ICC, WB in Human, Rat |
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) Anti-Caveolin-1/CAV1 Antibody (monoclonal, 12C7) |
|||
| M00179-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-MHC class 1 Rabbit Monoclonal Antibody |
|||
| M00194-1 | BosterBio | 100ug/vial | EUR 397 |
|
Description: Rabbit Monoclonal MHC class 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human. |
|||
 Anti-Integrin beta 1 Rabbit Monoclonal Antibody |
|||
| M00772-1 | BosterBio | 100ug/vial | EUR 397 |
|
Description: Rabbit Monoclonal Integrin beta 1 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat. |
|||
 Monoclonal Antibody (2E12)) Anti-Apaf-1 (human) Monoclonal Antibody (2E12) |
|||
| M00889-1 | BosterBio | 100ug | EUR 432 |
|
Description: Rat Monoclonal Apaf-1 (human) Antibody (2E12). Validated in ELISA, IP, IF, WB and tested in Human. |
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 Anti-ARG1/Arginase 1 Rabbit Monoclonal Antibody |
|||
| M01106-1 | BosterBio | 100ug/vial | EUR 397 |
|
Description: Rabbit Monoclonal ARG1/Arginase 1 Antibody. Validated in IP, WB and tested in Human, Mouse, Rat. |
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 Anti-MLANA/Mart 1 Rabbit Monoclonal Antibody |
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| M02033-1 | BosterBio | 100ug/vial | EUR 397 |
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Description: Rabbit Monoclonal MLANA/Mart 1 Antibody. Validated in IF, WB and tested in Human. |
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) Anti-TCP-1α Monoclonal Antibody (91a) |
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| M02389-1 | BosterBio | 200ug | EUR 498 |
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Description: Rat Monoclonal TCP-1α Antibody (91a). Validated in Flow Cytometry, IP, IF, WB and tested in Human, Mouse, Rat. |
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 Anti-DSG1/Desmoglein 1 Rabbit Monoclonal Antibody |
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| M02655-1 | BosterBio | 100ug/vial | EUR 397 |
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Description: Rabbit Monoclonal DSG1/Desmoglein 1 Antibody. Validated in IF, IHC, ICC, WB and tested in Human, Mouse, Rat. |
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 Antibody) Anti-Phospho-Glycogen Synthase 1 (S645) Antibody |
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| P03512-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for Phospho-Glycogen Synthase 1 (S645) Antibody (GYS1) detection.tested for WB in Human, Mouse, Rat. |
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) Anti-Musashi 1/Msi1 Antibody (monoclonal, 2B9) |
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| M05052-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-Visinin-like Protein 1 Monoclonal Antibody |
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| M06959-1 | BosterBio | 100ul | EUR 397 |
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Description: Mouse Monoclonal Visinin-like Protein 1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
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) StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible) |
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| CBA-325 | Cell Biolabs | 96 assays | EUR 856 |
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Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis. |
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StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible) |
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| CBA-325-5 | Cell Biolabs | 5 x 96 assays | EUR 3361 |
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Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis. |
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; Clone QBEnd/10 (Concentrate)) CD34 (Hematopoietic Stem Cell & Endothelial Marker); Clone QBEnd/10 (Concentrate) |
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| RA0052-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125 |
; Clone HPCA1/763 (Concentrate)) CD34 (Hematopoietic Stem Cell & Endothelial Marker); Clone HPCA1/763 (Concentrate) |
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| RA0053-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125 |
; Clone GA-5 (Concentrate)) GFAP (Astrocyte & Neural Stem Cell Marker); Clone GA-5 (Concentrate) |
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| RA0121-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125 |
; Clone ASTRO/789 (Concentrate)) GFAP (Astrocyte & Neural Stem Cell Marker); Clone ASTRO/789 (Concentrate) |
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| RA0122-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125 |
 (Pancreatic Stem Cell Marker); Clone BA17 (Concentrate)) Cytokeratin 19 (KRT19) (Pancreatic Stem Cell Marker); Clone BA17 (Concentrate) |
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| RA0191-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125 |
Additional evaluation confirmed that mC-1 of SLC4A11 and MFSD3 was situated in transcription issue binding websites for NF-1 and Sp1. Our findings revealed the novel organic capabilities of porcine SLC4A11 and MFSD3 genes in regulating the cytotoxic results induced by DON, and will contribute to the detection of biomarkers and drug targets for predicting and eliminating the potential toxicity of DON.