Basal cell carcinoma (BCC) is a major public well being concern, with greater than three million circumstances occurring every year in america, and with an growing incidence. The molecular foundation of BCC is advanced, involving an interaction of inherited genetic susceptibility, together with single nucleotide polymorphisms and genetic syndromes, and sporadic somatic mutations, typically induced by carcinogenic publicity to UV radiation.
This overview outlines the presently recognized germline and somatic mutations implicated within the pathogenesis of BCC, together with the important thing molecular pathways affected by these mutations, which drive oncogenesis. With advances in subsequent era sequencing and our understanding of the molecular genetics of BCC, established and rising focused therapeutics are providing new avenues for the non-surgical remedy of BCC. These brokers, together with Hedgehog pathway inhibitors, immune modulators, and histone deacetylase inhibitors, may even be mentioned.
XIAP gene remedy results on retinal ganglion cell construction and performance in a mouse mannequin of glaucoma
Glaucoma is a prevalent neurodegenerative illness that’s characterised by progressive visible discipline loss. It’s the main reason for irreversible blindness on the planet. The primary danger issue for glaucoma is elevated intraocular stress that leads to the injury and loss of life of retinal ganglion cells (RGCs) and their axons. The loss of life of RGCs has been proven to be apoptotic. We examined the speculation that blocking the activation of apoptosis could also be an efficient technique to forestall RGC loss of life and protect practical imaginative and prescient in glaucoma.
Within the magnetic microbead mouse mannequin of induced ocular hypertension, inhibition of RGC apoptosis was focused via viral-mediated ocular supply of the X-linked inhibitor of apoptosis (XIAP) gene, a potent caspase inhibitor. Sample electroretinograms revealed that XIAP remedy resulted in important safety of each somal and axonal RGC operate in glaucomatous eyes. Histology confirmed that the handled optic nerves confirmed preservation of axon counts and decreased glial cell infiltration. These outcomes present that XIAP is ready to present each practical and structural safety of RGCs within the microbead mannequin of glaucoma and supply vital proof-of-principle for XIAP’s efficacy as a neuroprotective remedy for glaucoma.
Major Mediastinal B-Cell Lymphoma: A 2021 Replace on Genetics, Prognosis, and Novel Therapeutics
Major mediastinal massive B-cell lymphoma (PMBCL) is an aggressive B-cell lymphoma arising from thymic B-cells having clinicopathologic options distinct from systemic diffuse massive B-cell lymphoma (DLBCL). PMBCL contains 2% to 4% of all non-Hodgkin lymphomas (NHL), 7% of DLBCL and seen predominantly in younger females with a median age of 35 years at analysis. The annual incidence of PMBCL is 0.Four per million with a 5-year survival charge exceeding 70% with enhancing supportive care and genetic characterization of the illness.
Pathogenesis entails dysregulation of Janus kinase-signal transducer and activator of transcription (JAK-STAT), nuclear factor-kB (NF-kB) pathways and amplification of the 9p24.1 area of chromosome 9. PMBCL sufferers have a protracted life expectancy necessitating the necessity for remedy approaches which can be based mostly on maximizing remedy with minimal long-term toxicity. Because of rarity and its recognition as a definite entity, therapeutic choices are guided by medical presentation, clinician and heart expertise, and evaluation of sufferers with PMBCL inside DLBCL registries.
Traditionally R-CHOP has been the standard first line remedy for PMBCL adopted by concerned web site radiotherapy (ISRT), nonetheless medical observe varies throughout facilities with rising consensus to keep away from upfront RT by using dose intense regimens (DA-EPOCH-R) in youthful and match sufferers. Prognosis of relapsed refractory PMBCL not responding to salvage chemotherapy is dismal, nonetheless there are a lot of rising choices together with Brentuximab Vedotin, immune examine level inhibitors and chimeric antigen receptor T-cell remedy. On this article, we concentrate on the pathogenesis, present and evolving therapies, and supply suggestions for optimum administration of sufferers with PMBCL.
PE38-based gene remedy of HER2-positive breast most cancers stem cells by way of VHH-redirected polyamidoamine dendrimers
Breast most cancers stem cells (BCSCs) resist standard therapies and trigger tumor recurrence. Nearly 25% of breast cancers overexpress human epidermal development issue receptor-2 (HER2). Right here we developed a novel multi-targeted nanosystem to particularly eradicate HER2+ BCSCs. Plasmids containing CXCR1 promoter, PE38 toxin, and 5’UTR of the fundamental fibroblast development factor-2 (bFGF 5’UTR) had been constructed. Polyamidoamine (PAMAM) dendrimers functionalized with anti-HER2 VHHs had been used for plasmid supply.
Stem cell proportion of MDA-MB-231, MDA-MB-231/HER2+ and MCF-10A had been evaluated by mammosphere formation assay. Hanging drop method was used to supply spheroids. The uptake, gene expression, and killing efficacy of the multi-targeted nanosystem had been evaluated in each monolayer and spheroid tradition. MDA-MB-231/HER2+ had increased capability to kind mammosphere in comparison with MCF-10A.
Our multi-targeted nanosystem effectively inhibited the mammosphere formation of MDA-MB-231 and MDA-MB-231/HER2+ cells, whereas it was unable to forestall the mammosphere formation of MCF-10A. Within the hanging drop tradition, MDA-MB-231/HER+ generated compact well-rounded spheroids, whereas MCF-10A did not kind compact mobile plenty.
 Betacellulin, human |
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| RC218-23 | Bio Basic | 5ug | EUR 104.38 |
 Rabbit Polyclonal antibody Anti-CRBN |
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| Anti-CRBN | ImmunoStep | 50 µg | EUR 349 |
 Anti-Betacellulin/Btc Antibody |
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| A02171-1 | BosterBio | 100ug/vial | EUR 334 |
 Recombinant Human Betacellulin |
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| 7-00223 | CHI Scientific | 5µg | Ask for price |
Recombinant Human Betacellulin |
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| 7-00224 | CHI Scientific | 20µg | Ask for price |
Recombinant Human Betacellulin |
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| 7-00225 | CHI Scientific | 1mg | Ask for price |
 Betacellulin antibody |
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| 70R-BR013 | Fitzgerald | 50 ug | EUR 273 |
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Description: Affinity purified Rabbit polyclonal Betacellulin antibody |
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 Betacellulin protein |
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| 30R-AB028 | Fitzgerald | 20 ug | EUR 273 |
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Description: Purified recombinant Human Betacellulin protein |
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 Betacellulin, Mouse |
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| HY-P7329 | MedChemExpress | 50ug | EUR 612 |
 Bovine Betacellulin |
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| ARU020 | GroPep | 20 µg | EUR 253 |
Bovine Betacellulin |
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| ARU100 | GroPep | 100 µg | EUR 346 |
， Human) Betacellulin (HEK293-expressed)， Human |
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| HY-P7328 | MedChemExpress | 10ug | EUR 234 |
 Protein) Human Betacellulin (bTC) Protein |
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| 20-abx065524 | Abbexa |
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 Recombinant Human Betacellulin Protein |
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| PROTP35070-2 | BosterBio | 20ug | EUR 317 |
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Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. |
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 Polyclonal Goat anti-GST α-form |
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| GST-ANTI-1 | Detroit R&D | 50 uL | EUR 280 |
 Polyclonal Goat anti-GST μ-form |
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| GST-ANTI-2 | Detroit R&D | 50 uL | EUR 280 |
 Polyclonal Goat anti-GST p-form |
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| GST-ANTI-3 | Detroit R&D | 50 uL | EUR 280 |
 Betacellulin, Murine Recombinant |
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| 7119-10 | Biovision | EUR 196 | |
Betacellulin, Murine Recombinant |
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| 7119-50 | Biovision | EUR 675 | |
) Recombinant Betacellulin (bTC) |
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| 4-RPA112Hu01 | Cloud-Clone |
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Description: Recombinant Human Betacellulin expressed in: E.coli |
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Recombinant Betacellulin (bTC) |
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| 4-RPA112Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Betacellulin expressed in: E.coli |
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 Antibody) Betacellulin (BTC) Antibody |
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| 20-abx111218 | Abbexa |
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 Antibody) Betacellulin (bTC) Antibody |
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| 20-abx100739 | Abbexa |
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Betacellulin (bTC) Antibody |
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| 20-abx100740 | Abbexa |
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 Recombinant Bovine Betacellulin |
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| 7-00226 | CHI Scientific | 5µg | Ask for price |
Recombinant Bovine Betacellulin |
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| 7-00227 | CHI Scientific | 20µg | Ask for price |
Recombinant Bovine Betacellulin |
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| 7-00228 | CHI Scientific | 1mg | Ask for price |
Betacellulin (bTC) Antibody |
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| 20-abx171411 | Abbexa |
|
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Betacellulin (BTC) Antibody |
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| abx230883-100ug | Abbexa | 100 ug | EUR 481 |
Betacellulin (bTC) Antibody |
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| 20-abx175568 | Abbexa |
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Betacellulin (bTC) Antibody |
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| 20-abx175569 | Abbexa |
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Betacellulin (bTC) Antibody |
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| 20-abx175570 | Abbexa |
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Betacellulin (bTC) Antibody |
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| 20-abx175571 | Abbexa |
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) Betacellulin, murine (mouse) |
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| RC238-23 | Bio Basic | 5ug | EUR 104.38 |
 ELISA Kit) Human Betacellulin (bTC) ELISA Kit |
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| SEA112Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 4273.35 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
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Human Betacellulin (bTC) ELISA Kit |
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| SEA112Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 439.57 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
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Human Betacellulin (bTC) ELISA Kit |
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| SEA112Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 585.1 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
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Human Betacellulin (bTC) ELISA Kit |
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| SEA112Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 2332.95 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
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Human Betacellulin (bTC) ELISA Kit |
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| 4-SEA112Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Betacellulin (bTC) in samples from Serum, plasma, tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species. |
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 Polyclonal Antibody (Human)) Betacellulin (bTC) Polyclonal Antibody (Human) |
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| 4-PAA112Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC) |
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 Human Betacellulin/BTC ELISA Kit |
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| LF-EK50996 | Abfrontier | 1×96T | EUR 648 |
 ELISA Kit) Human Betacellulin (BTC) ELISA Kit |
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| abx570040-96tests | Abbexa | 96 tests | EUR 668 |
 Human Betacellulin, BTC ELISA Kit |
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| DEIA089 | Creative Diagnostics | 10 plates | EUR 2605 |
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Description: This assay is a sandwich Enzyme Linked-Immuno-Sorbent Assay (ELISA). It is developed for quantitative measurement of human BTC in serum, plasma and other biological fluids. |
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 CLIA Kit) Human Betacellulin (BTC) CLIA Kit |
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| 20-abx491043 | Abbexa |
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 CLIA Kit) Human Betacellulin (bTC) CLIA Kit |
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| abx196482-96tests | Abbexa | 96 tests | EUR 825 |
Human Betacellulin (BTC) ELISA Kit |
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| abx250182-96tests | Abbexa | 96 tests | EUR 668 |
Human Betacellulin (bTC) ELISA Kit |
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| DLR-bTC-Hu-48T | DL Develop | 48T | EUR 479 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
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Human Betacellulin (bTC) ELISA Kit |
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| DLR-bTC-Hu-96T | DL Develop | 96T | EUR 621 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
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Human Betacellulin (bTC) ELISA Kit |
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| RD-bTC-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 478 |
Human Betacellulin (bTC) ELISA Kit |
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| RD-bTC-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 662 |
 BTC Betacellulin Human Recombinant Protein |
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| PROTP35070-1 | BosterBio | Regular: 20ug | EUR 317 |
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Description: Betacellulin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 80 amino acids and having a molecular mass of 9 kDa. ;Betacellulin Human Recombinant is purified by proprietary chromatographic techniques. |
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Human Betacellulin (bTC) ELISA Kit |
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| RDR-bTC-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 500 |
Human Betacellulin (bTC) ELISA Kit |
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| RDR-bTC-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 692 |
 Protein (Active)) Human Betacellulin (bTC) Protein (Active) |
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| 20-abx655563 | Abbexa |
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 ELISA Kit) Human BTC(Betacellulin) ELISA Kit |
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| EH0044 | FN Test | 96T | EUR 524.1 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
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, Mouse) Betacellulin (HEK293-expressed), Mouse |
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| HY-P7142 | MedChemExpress | 50ug | EUR 533 |
) Rat Betacellulin antiserum (Rabbit) |
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| PAAQ1 | GroPep | 100 µl | EUR 299 |
) Bovine Betacellulin antiserum (Rabbit) |
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| PAAR1 | GroPep | 100 µl | EUR 299 |
 Protein) Mouse Betacellulin (bTC) Protein |
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| 20-abx065525 | Abbexa |
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 Antibody (FITC)) Betacellulin (bTC) Antibody (FITC) |
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| 20-abx274036 | Abbexa |
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 Antibody (Biotin)) Betacellulin (bTC) Antibody (Biotin) |
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| 20-abx271925 | Abbexa |
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Betacellulin (bTC) Antibody (Biotin) |
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| 20-abx272658 | Abbexa |
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 Recombinant Murine Betacellulin Protein |
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| PROTQ05928-1 | BosterBio | 20ug | EUR 317 |
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Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant murine Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. |
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 Protein) Rat Betacellulin (bTC) Protein |
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| 20-abx652663 | Abbexa |
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 Protein) Cow Betacellulin (bTC) Protein |
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| 20-abx652665 | Abbexa |
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 Protein) Chicken Betacellulin (bTC) Protein |
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| 20-abx652666 | Abbexa |
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 Polyclonal Antibody (Human), APC) Betacellulin (bTC) Polyclonal Antibody (Human), APC |
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| 4-PAA112Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with APC. |
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 Polyclonal Antibody (Human), Biotinylated) Betacellulin (bTC) Polyclonal Antibody (Human), Biotinylated |
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| 4-PAA112Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with Biotin. |
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 Polyclonal Antibody (Human), Cy3) Betacellulin (bTC) Polyclonal Antibody (Human), Cy3 |
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| 4-PAA112Hu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with Cy3. |
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 Polyclonal Antibody (Human), FITC) Betacellulin (bTC) Polyclonal Antibody (Human), FITC |
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| 4-PAA112Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with FITC. |
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 Polyclonal Antibody (Human), HRP) Betacellulin (bTC) Polyclonal Antibody (Human), HRP |
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| 4-PAA112Hu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with HRP. |
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 Polyclonal Antibody (Human), PE) Betacellulin (bTC) Polyclonal Antibody (Human), PE |
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| 4-PAA112Hu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with PE. |
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) ELISA kit for Human bTC (Betacellulin) |
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| ELK1403 | ELK Biotech | 1 plate of 96 wells | EUR 432 |
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Description: A sandwich ELISA kit for detection of Betacellulin from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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) ELISA kit for Human BTC (Betacellulin) |
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| E-EL-H0570 | Elabscience Biotech | 1 plate of 96 wells | EUR 534 |
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Description: A sandwich ELISA kit for quantitative measurement of Human BTC (Betacellulin) in samples from Serum, Plasma, Cell supernatant |
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 Human Betacellulin/BTC PicoKine ELISA Kit |
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| EK0980 | BosterBio | 96 wells | EUR 425 |
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Description: For quantitative detection of human Betacellulin in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
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) CLIA kit for Human BTC (Betacellulin) |
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| E-CL-H0444 | Elabscience Biotech | 1 plate of 96 wells | EUR 584 |
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Description: A sandwich CLIA kit for quantitative measurement of Human BTC (Betacellulin) in samples from Serum, Plasma, Cell supernatant |
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 ELISA kit for Human Betacellulin/BTC |
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| EK5454 | SAB | 96 tests | EUR 553 |
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Description: Enzyme-linked immunosorbent assay kit for quantification of Human Betacellulin/BTC in samples from serum, plasma, tissue homogenates and other biological fluids. |
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) Human Probetacellulin [Cleaved into: Betacellulin protein (BTC) |
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| 1-CSB-EP002853HU | Cusabio |
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Description: Recombinant Human Probetacellulin [Cleaved into: Betacellulin protein(BTC) expressed in E.coli |
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 Polyclonal Antibody (Human), APC-Cy7) Betacellulin (bTC) Polyclonal Antibody (Human), APC-Cy7 |
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| 4-PAA112Hu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with APC-Cy7. |
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 BTC Betacellulin Human Recombinant Protein, His Tag |
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| PROTP35070 | BosterBio | Regular: 10ug | EUR 317 |
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Description: BTC Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 101 amino acids (32-111) and having a molecular mass of 11.3 kDa.;BTC is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
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 : 96 Wells (OKAG00006)) Betacellulin ELISA Kit (Human) : 96 Wells (OKAG00006) |
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| OKAG00006 | Aviva Systems Biology | 96 Wells | EUR 596 |
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Description: Description of target: This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 8 pg/mL |
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 ELISA Kit) Mouse Betacellulin (bTC) ELISA Kit |
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| SEA112Mu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 3710.48 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
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Mouse Betacellulin (bTC) ELISA Kit |
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| SEA112Mu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 393.22 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
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Mouse Betacellulin (bTC) ELISA Kit |
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| SEA112Mu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 518.88 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
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Mouse Betacellulin (bTC) ELISA Kit |
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| SEA112Mu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 2034.96 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
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Mouse Betacellulin (bTC) ELISA Kit |
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| 4-SEA112Mu | Cloud-Clone |
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|
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Betacellulin (bTC) in samples from Serum, plasma, tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
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 Polyclonal Antibody (Mouse)) Betacellulin (bTC) Polyclonal Antibody (Mouse) |
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| 4-PAA112Mu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC) |
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 Polyclonal Antibody (Rat)) Betacellulin (bTC) Polyclonal Antibody (Rat) |
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| 4-PAA112Ra01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC) |
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 ELISA Kit) Mouse Betacellulin (BTC) ELISA Kit |
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| 20-abx153708 | Abbexa |
|
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 ELISA Kit) Chicken Betacellulin (BTC) ELISA Kit |
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| abx574267-96tests | Abbexa | 96 tests | EUR 825 |
Mouse Betacellulin (BTC) ELISA Kit |
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| abx574631-96tests | Abbexa | 96 tests | EUR 668 |
 ELISA Kit) Cow Betacellulin (BTC) ELISA Kit |
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| abx575529-96tests | Abbexa | 96 tests | EUR 911 |
 ELISA Kit) Rat Betacellulin (BTC) ELISA Kit |
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| abx576495-96tests | Abbexa | 96 tests | EUR 825 |
 CLIA Kit) Mouse Betacellulin (BTC) CLIA Kit |
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| 20-abx491044 | Abbexa |
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Rat Betacellulin (BTC) ELISA Kit |
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| abx255590-96tests | Abbexa | 96 tests | EUR 668 |
Mouse Betacellulin (BTC) ELISA Kit |
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| abx253974-96tests | Abbexa | 96 tests | EUR 668 |
 ELISA Kit) Pig Betacellulin (BTC) ELISA Kit |
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| abx361663-96tests | Abbexa | 96 tests | EUR 825 |
 ELISA Kit) Rabbit Betacellulin (BTC) ELISA Kit |
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| abx363832-96tests | Abbexa | 96 tests | EUR 825 |
 ELISA Kit) Monkey Betacellulin (BTC) ELISA Kit |
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| abx359865-96tests | Abbexa | 96 tests | EUR 825 |
 BTC Betacellulin Bovine Recombinant Protein |
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| PROTQ9TTC5 | BosterBio | Regular: 20ug | EUR 317 |
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Description: Betacellulin Bovine Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 80 amino acids and having a molecular mass of 9003 Dalton. ;Betacellulin Bovine Recombinant is purified by proprietary chromatographic techniques. |
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Mouse Betacellulin (bTC) ELISA Kit |
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| DLR-bTC-Mu-48T | DL Develop | 48T | EUR 433 |
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Description: A sandwich quantitative ELISA assay kit for detection of Mouse Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
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Mouse Betacellulin (bTC) ELISA Kit |
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| DLR-bTC-Mu-96T | DL Develop | 96T | EUR 558 |
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Description: A sandwich quantitative ELISA assay kit for detection of Mouse Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
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 ELISA Kit) Rat Betacellulin (bTC) ELISA Kit |
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| DLR-bTC-Ra-48T | DL Develop | 48T | EUR 508 |
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Description: A sandwich quantitative ELISA assay kit for detection of Rat Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates,cell culture supernates or other biological fluids. |
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Rat Betacellulin (bTC) ELISA Kit |
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| DLR-bTC-Ra-96T | DL Develop | 96T | EUR 661 |
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Description: A sandwich quantitative ELISA assay kit for detection of Rat Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates,cell culture supernates or other biological fluids. |
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Mouse Betacellulin (bTC) ELISA Kit |
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| RD-bTC-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 426 |
Mouse Betacellulin (bTC) ELISA Kit |
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| RD-bTC-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 587 |
Rat Betacellulin (bTC) ELISA Kit |
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| RD-bTC-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 511 |
Rat Betacellulin (bTC) ELISA Kit |
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| RD-bTC-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 709 |
 BTC Betacellulin Mouse Recombinant Protein |
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| PROTQ05928 | BosterBio | Regular: 20ug | EUR 317 |
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Description: BTC Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 80 amino acids and having a molecular mass of 9.0kDa. ;The BTC is purified by proprietary chromatographic techniques. |
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Mouse Betacellulin (bTC) ELISA Kit |
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| RDR-bTC-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 445 |
Mouse Betacellulin (bTC) ELISA Kit |
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| RDR-bTC-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 614 |
Rat Betacellulin (bTC) ELISA Kit |
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| RDR-bTC-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 534 |
Rat Betacellulin (bTC) ELISA Kit |
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| RDR-bTC-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 742 |
 Recombinant Human BTC/ Betacellulin Protein, Untagged, E.coli-100ug |
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| QP10416-ec-100ug | EnQuireBio | 100ug | EUR 988 |
 Recombinant Human BTC/ Betacellulin Protein, Untagged, E.coli-20ug |
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| QP10416-ec-20ug | EnQuireBio | 20ug | EUR 290 |
 Recombinant Human BTC/ Betacellulin Protein, Untagged, E.coli-250ug |
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| QP10416-ec-250ug | EnQuireBio | 250ug | EUR 1731 |
 Recombinant Human BTC/ Betacellulin Protein, Untagged, E.coli-5ug |
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| QP10416-ec-5ug | EnQuireBio | 5ug | EUR 154 |
 Recombinant Human BTC/ Betacellulin Protein, His, E.coli-100ug |
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| QP5728-ec-100ug | EnQuireBio | 100ug | EUR 418 |
 Recombinant Human BTC/ Betacellulin Protein, His, E.coli-10ug |
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| QP5728-ec-10ug | EnQuireBio | 10ug | EUR 155 |
 Recombinant Human BTC/ Betacellulin Protein, His, E.coli-1mg |
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| QP5728-ec-1mg | EnQuireBio | 1mg | EUR 1678 |
 Recombinant Human BTC/ Betacellulin Protein, His, E.coli-200ug |
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| QP5728-ec-200ug | EnQuireBio | 200ug | EUR 635 |
 Recombinant Human BTC/ Betacellulin Protein, His, E.coli-500ug |
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| QP5728-ec-500ug | EnQuireBio | 500ug | EUR 1053 |
 Recombinant Human BTC/ Betacellulin Protein, His, E.coli-50ug |
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| QP5728-ec-50ug | EnQuireBio | 50ug | EUR 281 |
 Recombinant Human BTC/ Betacellulin Protein, His, Yeast-100ug |
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| QP5728-ye-100ug | EnQuireBio | 100ug | EUR 418 |
 Recombinant Human BTC/ Betacellulin Protein, His, Yeast-10ug |
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| QP5728-ye-10ug | EnQuireBio | 10ug | EUR 155 |
 Recombinant Human BTC/ Betacellulin Protein, His, Yeast-1mg |
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| QP5728-ye-1mg | EnQuireBio | 1mg | EUR 1678 |
 Recombinant Human BTC/ Betacellulin Protein, His, Yeast-200ug |
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| QP5728-ye-200ug | EnQuireBio | 200ug | EUR 635 |
 Recombinant Human BTC/ Betacellulin Protein, His, Yeast-500ug |
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| QP5728-ye-500ug | EnQuireBio | 500ug | EUR 1053 |
 Recombinant Human BTC/ Betacellulin Protein, His, Yeast-50ug |
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| QP5728-ye-50ug | EnQuireBio | 50ug | EUR 281 |
) Recombinant Mouse Betacellulin/BTC (N-6His) |
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| C747-10ug | Novoprotein | 10ug | EUR 156 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
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Recombinant Mouse Betacellulin/BTC (N-6His) |
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| C747-1mg | Novoprotein | 1mg | EUR 2283 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
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Recombinant Mouse Betacellulin/BTC (N-6His) |
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| C747-500ug | Novoprotein | 500ug | EUR 1613 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
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Recombinant Mouse Betacellulin/BTC (N-6His) |
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| C747-50ug | Novoprotein | 50ug | EUR 369 |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
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 Polyclonal Antibody (Mouse), APC) Betacellulin (bTC) Polyclonal Antibody (Mouse), APC |
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| 4-PAA112Mu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with APC. |
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 Polyclonal Antibody (Mouse), Biotinylated) Betacellulin (bTC) Polyclonal Antibody (Mouse), Biotinylated |
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| 4-PAA112Mu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with Biotin. |
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 Polyclonal Antibody (Mouse), Cy3) Betacellulin (bTC) Polyclonal Antibody (Mouse), Cy3 |
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| 4-PAA112Mu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with Cy3. |
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 Polyclonal Antibody (Mouse), FITC) Betacellulin (bTC) Polyclonal Antibody (Mouse), FITC |
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| 4-PAA112Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with FITC. |
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 Polyclonal Antibody (Mouse), HRP) Betacellulin (bTC) Polyclonal Antibody (Mouse), HRP |
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| 4-PAA112Mu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with HRP. |
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 Polyclonal Antibody (Mouse), PE) Betacellulin (bTC) Polyclonal Antibody (Mouse), PE |
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| 4-PAA112Mu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with PE. |
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 Polyclonal Antibody (Rat), APC) Betacellulin (bTC) Polyclonal Antibody (Rat), APC |
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| 4-PAA112Ra01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with APC. |
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 Polyclonal Antibody (Rat), Biotinylated) Betacellulin (bTC) Polyclonal Antibody (Rat), Biotinylated |
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| 4-PAA112Ra01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with Biotin. |
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 Polyclonal Antibody (Rat), Cy3) Betacellulin (bTC) Polyclonal Antibody (Rat), Cy3 |
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| 4-PAA112Ra01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with Cy3. |
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 Polyclonal Antibody (Rat), FITC) Betacellulin (bTC) Polyclonal Antibody (Rat), FITC |
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| 4-PAA112Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with FITC. |
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 Polyclonal Antibody (Rat), HRP) Betacellulin (bTC) Polyclonal Antibody (Rat), HRP |
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| 4-PAA112Ra01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with HRP. |
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 Polyclonal Antibody (Rat), PE) Betacellulin (bTC) Polyclonal Antibody (Rat), PE |
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| 4-PAA112Ra01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with PE. |
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) ELISA kit for Rat BTC (Betacellulin) |
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| E-EL-R0101 | Elabscience Biotech | 1 plate of 96 wells | EUR 534 |
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Description: A sandwich ELISA kit for quantitative measurement of Rat BTC (Betacellulin) in samples from Serum, Plasma, Cell supernatant |
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) ELISA kit for Mouse bTC (Betacellulin) |
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| ELK1236 | ELK Biotech | 1 plate of 96 wells | EUR 372 |
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Description: A sandwich ELISA kit for detection of Betacellulin from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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) CLIA kit for Mouse BTC (Betacellulin) |
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| E-CL-M0133 | Elabscience Biotech | 1 plate of 96 wells | EUR 584 |
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Description: A sandwich CLIA kit for quantitative measurement of Mouse BTC (Betacellulin) in samples from Serum, Plasma, Cell supernatant |
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 Mouse Betacellulin/BTC PicoKine ELISA Kit |
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| EK1193 | BosterBio | 96 wells | EUR 425 |
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Description: For quantitative detection of mouse BTC in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
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) ELISA kit for Mouse BTC (Betacellulin) |
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| E-EL-M0181 | Elabscience Biotech | 1 plate of 96 wells | EUR 534 |
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Description: A sandwich ELISA kit for quantitative measurement of Mouse BTC (Betacellulin) in samples from Serum, Plasma, Cell supernatant |
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 ELISA Kit) Guinea pig Betacellulin (BTC) ELISA Kit |
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| abx357846-96tests | Abbexa | 96 tests | EUR 825 |
 (OKBB00530)) Betacellulin/BTC ELISA Kit (Mouse) (OKBB00530) |
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| OKBB00530 | Aviva Systems Biology | 96 Wells | EUR 505 |
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Description: Description of target: Betacellulin, also known as BTC is a protein that in humans is encoded by the BTC gene. This gene is mapped to 4q13.3. The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. It is the growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. This protein is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL |
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 ELISA kit for Mouse Betacellulin/BTC |
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| EK5523 | SAB | 96 tests | EUR 553 |
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Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Betacellulin/BTC in samples from serum, plasma, tissue homogenates and other biological fluids. |
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 ELISA kit for Rat Betacellulin/BTC |
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| EK5582 | SAB | 96 tests | EUR 553 |
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Description: Enzyme-linked immunosorbent assay kit for quantification of Rat Betacellulin/BTC in samples from serum, plasma, tissue homogenates and other biological fluids. |
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 Polyclonal Antibody (Mouse), APC-Cy7) Betacellulin (bTC) Polyclonal Antibody (Mouse), APC-Cy7 |
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| 4-PAA112Mu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with APC-Cy7. |
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 Polyclonal Antibody (Rat), APC-Cy7) Betacellulin (bTC) Polyclonal Antibody (Rat), APC-Cy7 |
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| 4-PAA112Ra01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with APC-Cy7. |
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 ELISA Kit) Mouse Betacellulin/BTC(Beta Cellulin) ELISA Kit |
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| EM0021 | FN Test | 96T | EUR 567.6 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 4.688pg/ml |
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 [Fc]) Recombinant Betacellulin Protein (Asp 32-Tyr 111) [Fc] |
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| VAng-1124Lsx-1mg | Creative Biolabs | 1 mg | EUR 6099 |
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Description: Human Betacellulin, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH11618) |
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Recombinant Betacellulin Protein (Asp 32-Tyr 111) [Fc] |
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| VAng-1124Lsx-50g | Creative Biolabs | 50 µg | EUR 1013 |
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Description: Human Betacellulin, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH11618) |
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 Betacellulin/BTC ELISA Kit| Mouse Beta Cellulin ELISA Kit |
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| EF012837 | Lifescience Market | 96 Tests | EUR 689 |
 anti-human CCR1 |
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| 20R-3028 | Fitzgerald | 200 ug | EUR 587 |
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Description: Goat anti-human CCR1 antibody |
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 anti-human RecQL4 |
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| AR05-PA0007 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to human RecQL4 |
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 Anti-Human IgG |
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| DB-173-0.1 | DB Biotech | 100 μl | EUR 212 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-173-0.2 | DB Biotech | 200 μl | EUR 298 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-173-0.5 | DB Biotech | 500 μl | EUR 384 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-173-1 | DB Biotech | 1 ml | EUR 613 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-173-RTU-15 | DB Biotech | 15 ml | EUR 355 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB-173-RTU-7 | DB Biotech | 7 ml | EUR 231 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB-174-0.1 | DB Biotech | 100 μl | EUR 212 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-174-0.2 | DB Biotech | 200 μl | EUR 298 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-174-0.5 | DB Biotech | 500 μl | EUR 384 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-174-1 | DB Biotech | 1 ml | EUR 613 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-174-RTU-15 | DB Biotech | 15 ml | EUR 355 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB-174-RTU-7 | DB Biotech | 7 ml | EUR 231 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB173RTU-15 | DB Biotech | 15 ml | EUR 355 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB173RTU-7 | DB Biotech | 7 ml | EUR 231 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB174RTU-15 | DB Biotech | 15 ml | EUR 355 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB174RTU-7 | DB Biotech | 7 ml | EUR 231 |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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 anti-human Albumin |
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| LF-PA10001 | Abfrontier | 100 ug | EUR 403 |
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Description: Rabbit polyclonal to human Albumin |
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 Anti-Procalcitonin antibody *Mouse anti-human, monoclonal * |
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| V100125 | AAT Bioquest | 50 ug | EUR 306 |
Anti-Procalcitonin antibody *Mouse anti-human, monoclonal * |
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| V100126 | AAT Bioquest | 1 mg | EUR 393 |
 Goat anti-Human anti-thrombin polyclonal antibody |
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| CABT-L487 | Creative Diagnostics | 500ug | EUR 715 |
 Sheep anti-Human anti-thrombin polyclonal antibody |
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| CABT-L488 | Creative Diagnostics | 500ug | EUR 663 |
Sheep anti-Human anti-thrombin polyclonal antibody |
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| CABT-L489 | Creative Diagnostics | 100ug | EUR 663 |
Sheep anti-Human anti-thrombin polyclonal antibody |
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| CABT-L490 | Creative Diagnostics | 100ug | EUR 663 |
Sheep anti-Human anti-thrombin polyclonal antibody |
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| CABT-L491 | Creative Diagnostics | 100ug | EUR 663 |
 ELISA Kit) Human anti AMPH(anti amphiphysin) ELISA Kit |
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| EH2621 | FN Test | 96T | EUR 524.1 |
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Description: Method of detection: Sandwich ELISA, Double Antigen;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
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 ELISA Kit) Human anti-TPO(anti-thrombopoietin) ELISA Kit |
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| EH4147 | FN Test | 96T | EUR 524.1 |
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Description: Method of detection: Sandwich ELISA, Double Antigen;Reacts with: Homo sapiens ;Sensitivity: 0.938 ng/ml |
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 ELISA Kit) Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| AEA465Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 5647.8 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| AEA465Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 552.76 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| AEA465Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 746.8 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| AEA465Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3060.6 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| 4-AEA465Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. |
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 Goat anti Human IgE |
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| 70R-IG015 | Fitzgerald | 1 mg | EUR 349 |
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Description: Affinity purified Goat anti Human IgE antibody |
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 Anti-human CD9 antibody |
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| A1500-50 | Biovision | EUR 465 | |
 Anti-human CD63 antibody |
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| A1502-50 | Biovision | EUR 490 | |
 Anti-human CD41 antibody |
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| A1503-50 | Biovision | EUR 468 | |
 Anti-human CD81 antibody |
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| A1504-50 | Biovision | EUR 468 | |
 Anti-human CD44 antibody |
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| A1505-50 | Biovision | EUR 468 | |
The multi-targeted nanosystem confirmed significantly better uptake, increased PE38 expression, and subsequent cell loss of life in MDA-MB-231/HER2+ in comparison with MCF-10A. Nevertheless, the efficacy of our focused toxin gene remedy was decrease in MDA-MB-231/HER2+ spheroids in contrast with that within the monolayer tradition. the mixture of the cell floor, transcriptional, and translational concentrating on elevated the stringency of the remedy.